Lek Bensedin rastvor za injekciju/infuziju sadrži propilenglikol i etanol (videti odeljak 4.four). Evropska agencija za lekove (EMA) je izdala preporuke za dnevne limite izloženosti ekscipijensu propilenglikolu u sledećim pedijatrijskim populacijama:
Lek Bensedin, rastvor za injekciju/infuziju sadrži propilenglikol i etanol. Ovo treba imati na umu kada je indikovana parenteralna primena benzodiazepina, naročito u visokim zapreminama (npr. kontinuirana infuzija
Simply because benzodiazepines have the next chance for misuse and can be routine-forming, Health care companies have a tendency to prescribe them cautiously. They could prescribe them only for use as wanted, not daily, and they may prescribe reduced doses or select benzodiazepines that aren’t as solid.
Fluvoksamin inhibira i CYP3A4 i CYP2C19 što dovodi do inhibicije oksidativnog metabolizma diazepama. Istovremena primena fluvoksamina produžava poluvreme eliminacije i povećava koncentraciju u plazmi (PIK) diazepama za približno 190%.
valproinska kiselina (lek za lečenje epilepsije i mentalnih oboljenja) može da uspori izlučivanje diazepama iz organizma i pojača njegovo dejstvo;
The primary works by using of Bensedin diazepam are to alleviate panic and to manage the distress caused by alcohol withdrawal. Also, diazepam can handle muscle spasms attributable to some neurological ailments which include cerebral palsy. Diazepam is additionally made use of to control seizures such as Those people because of epilepsy.
These prescription drugs also activate the identical receptors as benzodiazepines and bring about GABA release. On account of how they get the job done, these medicines are only in treating insomnia and related snooze Problems. They consist of:
If you experience another symptoms which you believe can be due to this drugs, talk to your doctor or pharmacist.
Usually do not out of the blue halt taking this medicine. If you wish to prevent using this medicine, talk about this with your prescriber to start with. They may let you know how To achieve this, typically by lessening the dose little by little to ensure any uncomfortable withdrawal effects are saved to the least.
Usporen metabolizam diazepama dovodi click here do produženja poluvremena eliminacije i povećanja koncentracije diazepama u plazmi. Usporena je eliminacija N-demetil metabolita diazepama, što može značajno pojačati sedativni efekat. Povećan je rizik od inhibicije CNS, npr. sedacije.
Lek Bensedin, rastvor here za injekciju/infuziju se takođe koristi za terapiju akutnih konvulzija uključujući epileptični position (standing epilepticus), konvulzije nastale usled trovanja i febrilne konvulzije.
Opioids must only be used by those they are prescribed for. Usually do not give your medication to anyone else. Getting bigger doses or more Repeated doses of opioid, may well boost the risk of habit. Overuse and misuse can lead to overdose and/or death.
VAŽNO UPOZORENJE: U cilju smanjenja verovatnoće pojave neželjenih reakcija u toku intravenske primene, injekcije treba primeniti sporo (1 mL/min).
respiratorne i kardiovaskularne funkcije. Istovremena primena sa narkotičkim analgeticima može pospešiti psihičku zavisnost zbog pojačavanja euforičnog efekta.